Alexandr Kornev : rechercher sur Z-Library

Année:

2009

Langue:

english

Fichier:

PDF, 513 KB

english, 2009

Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα Holoenzyme

Angela J. Boettcher, Jian Wu, Choel Kim, Jie Yang, Jessica Bruystens, Nikki Cheung, Juniper K. Pennypacker, Donald A. Blumenthal, Alexandr P. Kornev, Susan S. Taylor

Journal:

Brent W. Osborne, Jian Wu, Caitlin J. McFarland, Christian K. Nickl, Banumathi Sankaran, Darren E. Casteel, Virgil L. Woods Jr., Alexandr P. Kornev, Susan S. Taylor, Wolfgang R. Dostmann

Année:

2011

Langue:

english

Fichier:

PDF, 2.28 MB

english, 2011

Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication

Journal:

Journal of Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2011

A Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase Fold

Jie Yang, Jian Wu, Jon M. Steichen, Alexandr P. Kornev, Michael S. Deal, Sheng Li, Banumathi Sankaran, Virgil L. Woods Jr., Susan S. Taylor

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2012

PKA: Lessons learned after twenty years

Taylor, Susan S., Zhang, Ping, Steichen, Jon M., Keshwani, Malik M., Kornev, Alexandr P.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2013

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2013

PKA RIα Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex Disease

Bruystens, Jessica G.H., Wu, Jian, Fortezzo, Audrey, Kornev, Alexandr P., Blumenthal, Donald K., Taylor, Susan S.

Journal:

Hu, Jiancheng, Ahuja, Lalima G., Meharena, Hiruy S., Kannan, Natarajan, Kornev, Alexandr P., Taylor, Susan S., Shaw, Andrey S.

Année:

2014

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2014

Kinase Regulation by Hydrophobic Spine Assembly in Cancer

Journal:

Molecular and Cellular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 4.03 MB

english, 2015

Using Markov State Models to Develop a Mechanistic Understanding of Protein Kinase A Regulatory Subunit RIα Activation in Response to cAMP Binding

Boras, Britton W., Kornev, Alexandr, Taylor, Susan S., McCulloch, Andrew D.

Journal:

Journal of Biological Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 4.09 MB

english, 2014

Yet another "active" pseudokinase, Erb3

Susan S. Taylor and Alexandr P. Kornev

Journal:

Zhang, Ping, Kornev, Alexandr P., Wu, Jian, Taylor, Susan S.

Année:

2010

Langue:

english

Fichier:

PDF, 604 KB

english, 2010

Discovery of allostery in PKA signaling

Journal:

Biophysical Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2015

A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains

Kornev, Alexandr P., Taylor, Susan S., Ten Eyck, Lynn F., Ranganathan, Rama

Journal:

PLoS Computational Biology

Année:

2008

Langue:

english

Fichier:

PDF, 619 KB

english, 2008

Allostery through the computational microscope: cAMP activation of a canonical signalling domain

Malmstrom, Robert D., Kornev, Alexandr P., Taylor, Susan S., Amaro, Rommie E.

Journal:

Nature Communications

Année:

2015

Langue:

english

Fichier:

PDF, 2.67 MB

english, 2015

Integration of signaling in the kinome: Architecture and regulation of the αC Helix

Taylor, Susan S., Shaw, Andrey S., Kannan, Natarajan, Kornev, Alexandr P.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2015

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2015

An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes

Zhang, Ping, Ye, Feng, Bastidas, Adam C., Kornev, Alexandr P., Wu, Jian, Ginsberg, Mark H., Taylor, Susan S.

Journal:

Kornev, Alexandr P., Taylor, Susan S.

Année:

2015

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2015

Dynamics-Driven Allostery in Protein Kinases

Journal:

Trends in Biochemical Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 4.74 MB

english, 2015

Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF

Jiancheng Hu, Haiyang Yu, Alexandr P. Kornev, Jianping Zhao, Erin L. Filbert, Susan S. Taylor and Andrey S. Shaw

Journal:

Antal, Corina E., Callender, Julia A., Kornev, Alexandr P., Taylor, Susan S., Newton, Alexandra C.

Année:

2011

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2011

Intramolecular C2 Domain-Mediated Autoinhibition of Protein Kinase C βII

Journal:

Cell Reports

Année:

2015

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2015

Hydrogen reduction of98MoF6in RF discharge

Kornev, Roman A., Sennikov, Petr G., Konychev, Dmitry A., Potapov, Alexandr M., Chuvilin, Dmitry Yu., Yunin, Pavel A., Gusev, Sergey A., Naumann, Martin

Journal:

Journal of Radioanalytical and Nuclear Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2016

Protein-Ligand Interactions through the Computational Microscope: Allostery in a Canonical Signaling Domain

Malmstrom, Robert D., Kornev, Alexandr P., Taylor, Susan S., Amaro, Rommie E.

Journal:

Taylor, Susan S., Shaw, Andrey, Hu, Jiancheng, Meharena, Hiruy S., Kornev, Alexandr

Année:

2016

Langue:

english

Fichier:

PDF, 38 KB

english, 2016

Pseudokinases from a structural perspective

Journal:

Biochemical Society Transactions

Année:

2013

Langue:

english

Fichier:

PDF, 404 KB

english, 2013

The evolution of protein phosphorylation || Evolution of the eukaryotic protein kinases as dynamic molecular switches

Susan S. Taylor, Malik M. Keshwani, Jon M. Steichen and Alexandr P. Kornev

Journal:

Philosophical Transactions Biological Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 3.07 MB

english, 2012

Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer

Ahuja, Lalima G., Kornev, Alexandr P., McClendon, Christopher L., Veglia, Gianluigi, Taylor, Susan S.

Journal:

Kornev, Alexandr P., Taylor, Susan S.

Année:

2017

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2017

Fractal Nature of Protein Interior and its Implications for Protein Function

Journal:

P. Barros, Emília, Malmstrom, Robert D., Nourbakhsh, Kimya, Del Rio, Jason C., Kornev, Alexandr P., Taylor, Susan S., Amaro, Rommie E.

Année:

2017

Langue:

english

Fichier:

PDF, 57 KB

english, 2017

Electrostatic Interactions as Mediators in the Allosteric Activation of Protein Kinase A RIα

Journal:

Biochemistry

Année:

2017

Langue:

english

Fichier:

PDF, 23.72 MB

english, 2017

A dynamic hydrophobic core orchestrates allostery in protein kinases

Kim, Jonggul, Ahuja, Lalima G., Chao, Fa-An, Xia, Youlin, McClendon, Christopher L., Kornev, Alexandr P., Taylor, Susan S., Veglia, Gianluigi

Journal:

Science Advances

Année:

2017

Langue:

english

Fichier:

PDF, 4.60 MB

english, 2017

Divalent metal ions control activity and inhibition of protein kinases

Knape, Matthias J., Ballez, Mike, Burghardt, Nicole C., Zimmermann, Bastian, Bertinetti, Daniela, Kornev, Alexandr P., Herberg, Friedrich W.

Journal:

Metallomics

Année:

2017

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2017

A Catalytically-Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation

Meng, Yilin, Ahuja, Lalima G., Kornev, Alexandr P., Taylor, Susan S., Roux, Benoît

Journal:

Journal of Molecular Biology

Année:

2018

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2018

Self-organization, entropy and allostery

Kornev, Alexandr P.

Journal:

Biochemical Society Transactions

Année:

2018

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2018

An Allosteric Region of Src Tyrosine Kinase Allows for Stabilization of Its Active-Like Conformation

Ahuja, Lalima G., Meng, Yilin, Kornev, Alexandr P., Roux, Benoit, Taylor, Susan

Journal:

Meng, Yilin, Ahuja, Lalima G., Kornev, Alexandr P., Taylor, Susan S., Roux, Benoît

Année:

2018

Langue:

english

Fichier:

PDF, 42 KB

english, 2018

Corrigendum to “A Catalytically-Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation.” J. Mol. Biol. 430(6) (Mar 16 2018), 881–889

Journal:

Journal of Molecular Biology

Année:

2018

Langue:

english

Fichier:

PDF, 128 KB

english, 2018

Disordered Protein Kinase Regions in Regulation of Kinase Domain Cores

Gógl, Gergő, Kornev, Alexandr P., Reményi, Attila, Taylor, Susan S.

Journal:

Trends in Biochemical Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 3.47 MB

english, 2019

The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domain

Schmidt, Sven H., Knape, Matthias J., Boassa, Daniela, Mumdey, Natascha, Kornev, Alexandr P., Ellisman, Mark H., Taylor, Susan S., Herberg, Friedrich W.

Journal:

Pilo, Caila A., Kunkel, Maya T., Van, An-Angela N., Kobori, Evan K., Kornev, Alexandr P., Longman, Cheryl, Gorrie, George, Taylor, Susan S., Newton, Alexandra C.

Année:

2019

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2019

Impaired Autoinhibition of Protein Kinase CÎ³ in Spinocerebellar Ataxia Type 14

Journal:

Année:

2020

Fichier:

PDF, 47 KB

2020

Allostery Explained Through Synchronized Oscillators and Fractal Networks

Kornev, Alexandr P.

Journal: